Sylvia Santosa
Department of Exercise Science, Concordia University
Adresse: 7141 Sherbrooke Street West, L-SP 165-21,
Montréal, QC, H4B 1R6, Canada
514.848.2424 #5841



Concordia University – Department of Exercise Science


Post-Doctorat: Fellow Endocrinology & Nutrition, Endocrine Research Unit, Mayo Clinic
Doctorat: School of Dietetics and Human Nutrition
Université McGill
RD.: College of Dietitians of Ontario
McGill University Health Centers
Baccalauréat: Department of Applied Human Nutrition
University of Guelph


Weight is a concern of millions of Canadians both on an individual and societal level. Despite existing public policy and individual weight interventions, we are still “growing” as a population with more Canadians overweight than not.

The metabolic and cellular mechanisms of why some overweight individuals develop diseases while others do not are not fully understood. Furthermore, in people with diseases, such as cardiovascular disease and diabetes, we do not fully understand how obesity affects the progression or treatment. Obesity treatment itself remains ineffective as most people who lose weight eventually gain it back.

The goal of Dr. Santosa’s research program is to identify the long-term effects of obesity, from the cell to the entire body. Her research applies techniques in biology, physiology and nutrition to study the effects of obesity that contribute to weight gain and disease.

Results from Dr. Santosa’s research program will promote the development of better public health interventions from disease prevention to management.


  • Murphy J, Moullec G, Santosa S. Factors associated with adipocyte size reduction after weight loss interventions for overweight and obesity: a systemic review and meta-regression. Metabolism. 2016: accepted.
  • Santosa S, Bonnes S, Jensen MD. Acute female hypogonadism alters adipose tissue fatty acid storage factors and chylomicronemia. Journal of Clinical Endocrinology and Metabolism. 2016: epub.
  • Yang SQ, DeGuire JR, Agellon S, Lavery P, Mak I, Weiler HA, Santosa S§. Conjugated linoleic acid mitigates testosterone-related changes in body composition in male guinea pigs. Nutrition Research. 2016:36; 408-17.
  • Dam V, Sikdar T, Santosa S§. From Neutrophils to Macrophages: Differences in Regional Adipose Tissue Depots. Obesity Reviews. 2016:17; 1-17.
  • Santosa S§, Jensen MD. The sexual dimorphism of lipid kinetics in humans. Frontiers in Endocrinology. 2015: 6:103 (6 pages).
  • Hames KC, Koutsari C, Santosa S, Bush NC, Jensen MD. Adipose tissue fatty acid storage factors: effects of depot, sex and fat cell size. International Journal of Obesity. 2015:39; 884-7.
  • Varady KA*, Dam V*, Horne M, Cruz R, Klempel MC, Kroeger CM, Santosa S§. Effects of weight loss via high fat vs low fat alternate day fasting diets on free fatty acid profiles. Scientific Reports. 2015:5; 7561 (6 pages).
  • Santosa S, Swain J, Tchkonia T, Kirkland JL, Jensen MD. Inflammatory characteristics of adipose tissue collected by surgical excision vs. needle aspiration. International Journal of Obesity. 2015:39; 874-6.
  • Santosa S§, Jensen MD. Sex and sex steroids: impact on the kinetics of fatty acids underlying body shape. Hormone Molecular Biology and Clinical Investigation. 2014:20;15-23.
  • Du S, Rajjo T, Santosa S, Jensen MD. The thermic effect of food is reduced in older adults. Hormone and Metabolic Research. 2014:46;365-9.