GROUPE DE RECHERCHE EN ACTIVITÉ PHYSIQUE ADAPTÉE
MEMBRES
Tanja Taivassalo
McGill University
Department of Kinesiology and Physical Education (KPE) University Clinic
Royal Victoria Hospital
Montréal, Québec, Canada
Tel: (514) 398-4184 #0528
COURRIEL: tanja.taivassalo@mcgill.ca

PROFESSEUR

Kinesiology & Physical Education
Université McGill

FORMATION

Post-Doctorat en Exercise Pathophysiology
Inborn errors of metabolism
University of Texas at Dallas
Doctorat en Neurological Sciences Neuromuscular Disease
McGill University
Baccalauréat en Sciences Biologiques
Université McGill

INTÉRÊTS DE RECHERCHE

  • Mitochondrial disorders, Skeletal muscle metabolism, Adaptation to exercise

BIOGRAPHIE

Dr Taivassalo’s research has focused on the pathophysiology of skeletal muscle mitochondrial disorders and the safety and efficacy of exercise training in their treatment. Deleterious effects of physical inactivity superimposed upon impaired mitochondrial function contribute to varying degrees of exercise intolerance in these patients. Endurance exercise has potential to induce normal adaptive mitochondrial biogenesis thereby increasing levels of functional mitochondria, exercise tolerance and quality of life. The therapeutic potential of resistance training is based on a concept of gene shifting and relies on activation of muscle satellite cells to increase levels of functional muscle mitochondria.

Integrative methodologies in the laboratory including clinical exercise testing and gas exchange, MRI and spectropscopy, ultrasound and NIR, biochemical and molecular analyses are used to measure cardiovascular, pulmonary, metabolic and muscle responses to exercise and training. The idea that mitochondrial dysfunction may be central to aging and other chronic conditions make these ‘cellular powerhouses’ an energizing field of study!


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